Last of all, clonidine improves neuraxial opioids and, in combination with fentanyl, interacts within an additive manner, which may reduce the dose of every component by 60% for postoperative analgesia. Clonidine treats significant blood pressure level by stimulating α2 receptors while in the brainstem, which decreases peripheral vascular resistance, https://www.proleviate.com/post/the-new-pain-killer-conolidine