Objective: To compare intravenous Lignocaine with Dexmedetomidine for prevention of pressor response to laryngoscopy. Study design and setting: Randomized Clinical Trial at Anesthesia Department. RIHS Islamabad. (1st May2019 To 30th October 2019) Methodology: 68 patients with age 20-60 years. https://www.itsmajorlook.com/