Mesothelioma and Work Exposure Mesothelioma is more common for those who work with asbestos. Construction workers firefighters, military veterans or firefighters are especially vulnerable. The lung's lining (pleural mesothelioma), or the abdomen, is the primary site of mesothelioma. In rare instances, it may affect the testicles or the heart. See https://vimeo.com/704915343